- CAF (Cytoxan, Adriamycin and Fluorouracil) or FAC
- CEF (Cytoxan, Epirubicin and Fluorouracil) or FEC
- CMF (Cytoxan, Methotrexate and Fluorouracil)
Fluorouracil is given by vein. It is usually given in several cycles, with a day (or days) of treatment followed by a period of “off” days. The exact schedule depends on the medicines used. Most chemotherapy regimens consist of between four and six cycles of treatment given over 3 to 6 months.
Side effects may include:
- Loss of appetite
- Hand and foot syndrome
- Menopausal symptoms
- Mouth sores
- Nausea and vomiting
- Drop in white blood cells
- Taste changes
- Vision or eye problems
Before starting fluorouracil, tell your doctor about any medicines you are taking, including vitamins, herbal supplements and over-the-counter medicines. You should not take fluorouracil during the first trimester of pregnancy.
Your doctor will test your blood before and during treatment to check your white and red blood cell levels. Your liver and kidneys will also be checked.
Be sure to call your doctor right away if:
- you have chest pain, as this may be a sign of heart problems
- you have pain at the injection site, as this can be a sign of an allergic reaction
- you have a high fever, as this can be a sign of a serious infection