Words to Know
genome-wide association study
A study that compares the complete DNA of people with a disease or condition to the DNA of people without the disease or condition. These studies find the genes involved in a disease and may help prevent, diagnose and treat the disease. Also called GWAS, WGA study and whole genome association study.
Information about all the genes in an organism, including variations, gene expression and the way those genes interact with each other and with the environment. A genomic profile may be used to discover why some people get certain diseases while other people do not, or why people respond differently to the same medicine.
Good Clinical Practice
Also called GCP. An international set of guidelines that helps make sure that the results of a clinical trial are reliable and that the participants are protected. Good Clinical Practice covers the way a clinical trial is designed, conducted, performed, monitored, audited, recorded, analyzed and reported.
A system for classifying cancer cells in terms of how abnormal they appear when examined under a microscope. The objective of a grading system is to provide information about the probable growth rate of the tumor and its tendency to spread. The systems used to grade tumors vary with each type of cancer. Grading plays a role in treatment decisions.